Aquaponics: Farming Fish and Growing Greens for Grades 9–12 teaches STEM-related course material through aquaponics, a water-based agricultural system that combines aquaculture (fish production) and hydroponics (soilless vegetable production) systems. This curriculum is aligned with Next Generation Science Standards and designed to be used with an onsite aquaponics system. Topics include an introduction to aquaculture, fundamental parts of an aquaponics system, the nitrogen cycle, water quality, population dynamics, our modern food system, and more. The ten lessons presented build on each other and are intended to be delivered in sequential order. Alternatively, lessons may also be utilized as stand-alone units to supplement other curricular activities.