This book provides comprehensive knowledge and recent advancements in biotic stress tolerance in crop plants. Despite this, it also focuses on the relevance of these advancements in securing food for the future. Rapid population outburst along with the significant reduction in agricultural fields across the globe embarks a serious threat to meet the need for the foods for the future. Yield loss due to biotic ingression makes the situation more complicated. Rapid climate change also has altered pathogenesis in many common crop plants. In this regard, a systematic and comprehensive approach is urgently necessary for sustainable agricultural developments. The biotic stress tolerance in crop plants is distinct from that of model plants hence, demands more priority. Host-microbe interaction is a very interesting branch of research in plant science. Although many host-microbe systems had extensively been studied, the systematic assemblage of the same with crop plants is largely obscured. Additionally, the implication of all these techniques in employing food security of the mass is again scarce. Given the above, the present book tries to fill the gap of knowledge to facilitate the "e;lab-to-land transition"e; of the same. The chapters are designed to cover all the aspects related to crop plant biotic stress tolerance mechanism in the light of modern biotechnology and the implication of the same in food security. The in-depth information provided in different chapters not only improves knowledge in biotic stress in crop plants but endow future research in this field also.