The Malediction Plague follows the disturbing journey of Dr. Leon Fleischer, a medical scientist whose research inadvertently leads to the creation of a devastating plague that transforms people into zombie-like creatures. Dismayed by his fiancée ending their engagement, Leon spirals into an ominous state of mind, playing god although also yearning for the approval of haunting paternal figureheads who raised him with a sense of superiority. As chaos engulfs the city, Leon grapples with slow-growing guilt and a sense of responsibility for unleashing horror upon the world while wrestling his internal demons and extraordinary ego. Is there hope for humanity given this new reality of gore and mayhem?