Set in the early 1980s, The Point of Life is the story of a young man from a small town in Kansas named Endicott "Endy" Mason. After being raised in a small farming community, a teenage Endy moves with his family to the big city of Indianapolis, Indiana. Feeling insecure about his upbringing, Endy develops goals for his life that include rising high in the corporate ranks and making a lot of money.

While on the high school baseball team, Endy pitches a no-hitter, and this helps him gain popularity in his class along with the attention of a teammate's wealthy father who offers to assist him in gaining a scholarship to a notable college program. Endy's newfound popularity also earns him the affection of Stephanie Plum, the prettiest girl in the school. The relationship goes well at first, but when Stephanie goes off to college, Endy betrays a good friend and cheats on her, effectively killing his first real relationship.

Vowing to be a better person, Endy strikes up an unlikely friendship with a fellow college teammate named Dez, who is Black. The two become very close over the years, but a tragedy ends their friendship at a pivotal time in Endy's life. He is about to get married to a very wealthy girl named Layla whose family is not too keen on Endy's good friend being his best man. With Endy's business career in full bloom, he faces other issues that lead him to reevaluate his goals and aspirations. From working for bad managers to being asked to follow unethical decisions, Endy learns valuable lessons about what really matters and in the process influences others around him to see life from a different perspective.