Stem cells are immature, undifferentiated cells that can divide and multiply for an extended period of time, differentiating into specific types of cells and tissues.They are defined as cells that self replicate and are able to differentiate into at least two different cell types. Both criteria must be present for a cell to be called a ¿stem cell.¿ Discoveries in stem cell research presents an opportunity for scientific evidences that stem cells, whether derived from adult tissues or the earliest cellular forms hold great promise that go far beyond regenerative medicine. Recent studies have shown that Stem cells from human exfoliated deciduous teeth (SHED) have the ability to develop into various types of body tissues than other types of stem cells.Dentists are at the forefront of engaging their patients in potentially life-saving therapies derived from their own stem cells located either in deciduous or permanent teeth.